Yes, but they need to be done at least twice a week to get an on-going benefit. As the benefit of masks are very short lived.
Also you should make sure you're applying the correct mask in the correct section of your skin as a lot of the time people can have reactions and this is simply because the mask they're applying isn't for that part of the skin type/problem. For example if I have sensitive cheeks but acne on my chin I won't apply an acne/ clay mask on my cheeks because that sensitive area will become red and irritated and therefore potentially causing a whole load of other problems!
I always recommend multi-masking which is applying 2 or more different masks in different areas to solve different skin problems.
Here is the lowdown and what ingredients you should look for in your products for different concerns.